Guerrero Jr. hit a long solo ball in the first inning. Two innings later, he drove in another run on an optional. The 23-year-old’s first baseman homer was his 28th homer this year. It ended a drought of 14 games without a cannon shot.
Bo Bichette, Santiago Espinal and Raimel Tapia added one-run singles for the Jays, leaders of the trio of clubs that would reach the playoffs without being division champions, in the American.
Toronto leads Seattle by a half game and Tampa Bay by a game and a half.
Bichette has produced 15 runs in his last 10 games, posting a .465 batting average during that span.
Ross Stripling (8-4) allowed one run and three hits in six-and-a-third innings, striking out four batters. Coming out of the game, he was warmly greeted by the crowd of 24,282.
Adam Cimber, Yimi Garcia and Anthony Bass completed relief work.
Harold Ramirez homered in a losing cause, while Drew Rasmussen (10-5) allowed four runs and six hits in four innings.